Cat. #151499
Anti-CyclinB1 [PSA1.1]
Cat. #: 151499
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Cyclin B1
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jonathon Pines
Institute: University of Cambridge
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CyclinB1 [PSA1.1]
- Alternate name: CCNB1; Cyclin B1; G2/Mitotic-Specific Cyclin B1; CCNB
- Research fields: Cancer;Cell biology;Genetics
- Clone: PSA1.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: Cyclin B1 is involved in the regulation of cdk1, and the subsequent entry of eukaryotic cells into metaphase of the cell cycle. Cyclin B1 phosphorylates cdk1 at Thr14 and Tyr15, keeping cdk1 inactive. When cyclin B1 is inactivated by phosphorylation, cdc25 may then dephosphorylate Thr14 and Tyr15 of cdk1, allowing progression to metaphase.
- Immunogen: PSATGKVIDKKLPC
- Isotype: IgM
Target Details
- Target: Cyclin B1
- Target background: Cyclin B1 is involved in the regulation of cdk1, and the subsequent entry of eukaryotic cells into metaphase of the cell cycle. Cyclin B1 phosphorylates cdk1 at Thr14 and Tyr15, keeping cdk1 inactive. When cyclin B1 is inactivated by phosphorylation, cdc25 may then dephosphorylate Thr14 and Tyr15 of cdk1, allowing progression to metaphase.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
