Anti-Cdk1 [3E1.1]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-Cdk1 [3E1.1]
• Alternate name: Cyclin-Dependent Kinase 1; Cell Division Cycle 2, G1 To S And G2 To M; Cell Division Control Protein 2 Homolog; Cell Division Protein Kinase 1; P34 Protein Kinase; P34CDC2; CDC28A; CDC2; Cell Cycle Controller CDC2; CDKN1
• Research fields: Cancer;Cell biology;Neurobiology
• Clone: 3E1.1
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 175 kDa
• Strain: Balb/c
• Reactivity: Xenopus laevis
• Host: Mouse
• Application: WB
• Description: Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells.
• Immunogen: A carboxy-terminal fragment starting at methionine 85 of Xenopus laevis p34 cdc2.
• Isotype: IgG1
• Myeloma used: Sp2/0-Ag14

Target Details

• Target: Cyclin Dependent kinase 1 (Cdk1, Cdc2)
• Molecular weight: 175 kDa
• Target background: Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells.

Applications

• Application: WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Kobayashi et al. 1991. Cold Spring Harb Symp Quant Biol. 56:437-47. PMID: 1840257.
• Cyclins and their partners during Xenopus oocyte maturation.