Cdk1 is a marker for proliferating tumour cells.
| Inventor | Institute |
|---|---|
| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151049 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Neurobiology |
| Application: | WB |
| Target: | Cyclin Dependent kinase 1 (Cdk1, Cdc2) |
| Reactivity: | Xenopus laevis |
| Clone: | 3E1.1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Cyclin-Dependent Kinase 1; Cell Division Cycle 2, G1 To S And G2 To M; Cell Division Control Protein 2 Homolog; Cell Division Protein Kinase 1; P34 Protein Kinase; P34CDC2; CDC28A; CDC2; Cell Cycle Controller CDC2; CDKN1 |
|---|---|
| Product description: | Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 175 kDa |
| Immunogen: | A carboxy-terminal fragment starting at methionine 85 of Xenopus laevis p34 cdc2. |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Kobayashi et al. 1991. Cold Spring Harb Symp Quant Biol. 56:437-47. PMID: 1840257. Cyclins and their partners during Xenopus oocyte maturation. |
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