CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and neurons and glial cells in the peripheral nervous system. CD9 mediates platelet aggregation and activation via FCGR2a. It may play a role in cell migration.
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| University of Birmingham |
| Cat. #: | 151451 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology |
| Application: | FACS ; IHC ; IF ; IP ; WB |
| Target: | CD9 |
| Reactivity: | Human |
| Clone: | BU16 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and neurons and glial cells in the peripheral nervous system. CD9 mediates platelet aggregation and activation via FCGR2a. It may play a role in cell migration. |
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| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and neurons and glial cells in the peripheral nervous system. CD9 mediates platelet aggregation and activation via FCGR2a. It may play a role in cell migration. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Takeda et al. 2003. J Cell Biol. 161(5):945-56. PMID: 12796480. Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes. Funakoshi et al. 2003. Oncogene. 22(5):674-87. PMID: 12569360. Expression of tetraspanins in human lung cancer cells: frequent downregulation of CD9 and its contribution to cell motility in small cell lung cancer. Flora et al. 1994. Eur J Immunol. 24(11):2625-32. PMID: 7525298. Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage-specific monoclonal antibody. |
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