Anti-CD81 [2s141]

CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to […]

Contributors

Institute
University of Birmingham
Cat. #: 154263
Unit size: 100 ug
Research Fields: Immunology;Microbiology
Application: ELISA ; FACS ; IF ; WB
Target: CD81 and its second extracellular domain (EC2)
Reactivity: Human
Host: Mouse
Class: Monoclonal
Alternate name: 26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1, Tetraspanin-28
Product description: CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.
Conjugation: Unconjugated
Immunogen: P60033, CD81_HUMAN
Immunogen Uniprot ID: P60033, CD81_HUMAN
Myeloma used: NS0
Target background: CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.
Format: Liquid
Concentration: 0.9-1.1mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Tkachuk et al. 1975. FEBS Lett. 52(1):66-8. PMID: 1123084.

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