CD81 is co-opted during the life cycle of diversehuman pathogens: it is involved in hepatitis C virus (HCV) andPlasmodium sporozoite invasion of hepatocytes, and alsocontributes to the assembly and budding of human immunodeficiencyvirus and influenza A virus. Developed as a part of panel of murine monoclonalantibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.
| Institute |
|---|
| University of Birmingham |
| Cat. #: | 154236 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology;Microbiology |
| Application: | WB ; ELISA ; FACS ; IF |
| Target: | CD81 and its second extracellular domain (EC2) |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | 26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1, Tetraspanin-28 |
|---|---|
| Product description: | CD81 is co-opted during the life cycle of diversehuman pathogens: it is involved in hepatitis C virus (HCV) andPlasmodium sporozoite invasion of hepatocytes, and alsocontributes to the assembly and budding of human immunodeficiencyvirus and influenza A virus. Developed as a part of panel of murine monoclonalantibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection. |
| Conjugation: | Unconjugated |
| Immunogen: | P60033, CD81_HUMAN |
| Immunogen Uniprot ID: | P60033, CD81_HUMAN |
| Myeloma used: | NS0 |
| Target background: | CD81 is co-opted during the life cycle of diversehuman pathogens |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Tkachuk et al. 1975. FEBS Lett. 52(1):66-8. PMID: 1123084. |
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