CD45RA is an isoform of the CD45 complex which is selectively expressed on B cells.
| Inventor | Institute |
|---|---|
| Margaret Goodall | University of Birmingham |
| Cat. #: | 153226 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology;Stem cell biology |
| Application: | IHC |
| Target: | CD45RA |
| Reactivity: | Human |
| Clone: | BU82 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Protein tyrosine phosphatase receptor type C; PTPRC; |
|---|---|
| Product description: | CD45 is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45RA is an isoform of the CD45 complex which is selectively expressed on B cells. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Germinal centre B cells |
| Target background: | CD45 is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45RA is an isoform of the CD45 complex which is selectively expressed on B cells. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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