Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout.
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| Cat. #: | 153303 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction;Immunology;Stem cell biology |
| Application: | ELISA ; FACS ; IHC ; WB |
| Target: | T-cell surface glycoprotein CD3 gammadelta-A chain |
| Reactivity: | Salmon ; Rainbow Trout |
| Clone: | T1P1D4*C6 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD3, CD3gd, cd3g/d, cd3-gamma |
|---|---|
| Product description: | Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout. The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3γ, CD3δ and 2X CD3Ɛ), associates with the T cell antigen receptor (TCR). It is found on all mature human T lymphocytes, NK cells and some thymocytes. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. Anti-CD3 [T1P1D4*C6] is specific for CD3 in Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss). |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Ovalbumin-conjugated synthetic peptide- TLEYKDENTNEY |
| Immunogen Uniprot ID: | A3RK68 |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3γ, CD3δ and 2X CD3Ɛ), associates with the T cell antigen receptor (TCR). It is found on all mature human T lymphocytes, NK cells and some thymocytes. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. Anti-CD3 [T1P1D4*C6] is specific for CD3 in Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss). |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Immunohistochemical examination of immune cells in adipose tissue of rainbow trout (Oncorhynchus mykiss) following intraperitoneal vaccination. Veenstra et al. 2019. Fish Shellfish Immunol. 87:559-564. PMID: 30731214. Immunohistochemical examination of immune cells in adipose tissue of rainbow trout (Oncorhynchus mykiss) following intraperitoneal vaccination. |
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