Cat. #154728
Anti-CD27 [LG3A10]
Cat. #: 154728
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: CD27
Class: Monoclonal
Application: ELISA ; FACS ; IHC ; IP
Reactivity: Human ; Mouse
Host: Hamster
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD27 [LG3A10]
- Alternate name: Tumor Necrosis Factor Receptor Superfamily, Member 7; TNFRSF7
- Research fields: Cell signaling and signal transduction;Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 55 kDa
- Strain: Armenian
- Reactivity: Human ; Mouse
- Host: Hamster
- Application: ELISA ; FACS ; IHC ; IP
- Description: CD27 is a member of the tumour necrosis factor receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-ÄÂ?B and MAPK8/JNK
- Immunogen: Armenian hamster fibroblasts transfected with the mouse CD27 DNA. Screened on same transfectants.
- Isotype: IgG
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: CD27
- Molecular weight: 55 kDa
- Target background: CD27 is a member of the tumour necrosis factor receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-B and MAPK8/JNK
Applications
- Application: ELISA ; FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -20° C
- Shipping conditions: Dry ice
References
- Hendriks et al. 2000. Nat Immunol. 1(5):433-40. PMID: 11062504.
- Gravestein et al. 1996. J Exp Med. 184(2):675-85. PMID: 8760821.
- Gravestein et al. 1995. Int Immunol. 7(4):551-7. PMID: 7547681.
