Anti-CD25 [PC61 5.3]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-CD25 [PC61 5.3]
• Alternate name: Interleukin 2 Receptor Subunit Alpha; IL-2 Receptor Subunit Alpha; IL-2R Subunit Alpha; TAC Antigen; P55; Insulin-Dependent Diabetes Mellitus 1; CD25 Antigen
• Research fields: Biochemistry;Immunology
• Clone: PC61 5.3
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Reactivity: Mouse
• Host: Rat
• Application: FACS ; IHC ; IP
• Description: CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor Î? chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor Î? (CD122) and common Î? chains (CD132) to form the high affinity IL-2R complex.
• Isotype: IgG1

Target Details

• Target: CD25
• Target background: CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor a chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+T cells termed T regulatory cells. CD25 associates with the IL-2 receptor ? (CD122) and common ? chains (CD132) to form the high affinity IL-2R complex.

Applications

• Application: FACS ; IHC ; IP

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Lowenthal et al. 1985. J Immunol. 135(6):3988-94. PMID: 3934270.