MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain.
| Institute |
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| Netherlands Cancer Institute |
| Cat. #: | 154760 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Cancer types: | Breast cancer;Gynaecologic cancer |
| Research Fields: | Cancer;Cell signaling and signal transduction |
| Application: | EM (EM) ; ELISA ; FACS ; IHC ; IF ; IP ; WB |
| Target: | CD227 |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Mucin 1, Cell Surface Associated |
|---|---|
| Product description: | MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 120 kDa |
| Immunogen: | Milkfat globule membranes |
| Target background: | MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Hilkens et al. 1984. Int J Cancer. 34(2):197-206. PMID: 6206003. |
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