Cat. #151130
Anti-CD1c [M241] mAb
Cat. #: 151130
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: CD1c (Human Thymus Leukaemia antigen)
Class: Monoclonal
Application: IHC ; IP ; RIA
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Walter Bodmer
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD1c [M241] mAb
- Alternate name: CD1c Molecule; CD1C Antigen; C Polypeptide; CD1c Antigen; Differentiation Antigen CD1-Alpha-3; Cortical Thymocyte Antigen; CD1C; BDCA1; CD1A; CD1; R7
- Research fields: Cancer;Cell biology;Immunology
- Clone: M241
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 45 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP ; RIA
- Description: M241 is useful for identification and elimination of some leukaemias.
- Immunogen: MOLT 4 cell line
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: CD1c (Human Thymus Leukaemia antigen)
- Molecular weight: 45 kDa
- Target background: Cluster of Differentiation 1c (CD1c) is one of five human CD1 isoforms, a family of b2-microglobulin-associated transmembrane proteins that bind and present lipid antigens to T cells.
Applications
- Application: IHC ; IP ; RIA
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.
- Wen et al. 2016. J Immunol. :. PMID: 27296666.
- Small et al. 1989. Hum Immunol. 25(3):181-93. PMID: 2670851.
- Characterization of B cells in severe combined immunodeficiency disease.
- Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283.
- Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.
- Matsumoto et al. 1986. J Immunol. 137(9):2907-12. PMID: 2428878.
- Fn analysis of activated C1s, a subcomponent of the first component of human complement, by monoclonal antibodies.
- Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.
- A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin.
