Cat. #153413
Anti-CCT beta [PK/8/4/4i/2f]
Cat. #: 153413
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Mouse CCT2 / CCT Beta
Class: Monoclonal
Application: IHC ; WB
Reactivity: Bovine ; Dog ; Hamster ; Human ; Mouse ; Pig ; Rat ; Rabbit ; Sheep
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Keith Willison
Institute: The Institute of Cancer Research
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CCT beta [PK/8/4/4i/2f]
- Alternate name: CCT2; 99D8.1; CCT-beta; CCTB; PRO1633; TCP-1-beta; TCP1 Beta
- Research fields: Apoptosis and autophagy;Cancer;Cell biology;Immunology
- Clone: PK/8/4/4i/2f
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 55 kDa
- Strain: Balb/c
- Reactivity: Bovine ; Dog ; Hamster ; Human ; Mouse ; Pig ; Rat ; Rabbit ; Sheep
- Host: Rat
- Application: IHC ; WB
- Description: This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.
- Immunogen: TCP1 beta peptide conjugated to purified tuberculin protein derivative (PPD) (Mouse)
- Isotype: IgG2b
Target Details
- Target: Mouse CCT2 / CCT Beta
- Molecular weight: 55 kDa
- Target background: This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.
Applications
- Application: IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Satish et al. 2010. Cell Stress Chaperones. 15(6):819-26. PMID: 20393890.
- Cloning and expression of rabbit CCT subunits eta and beta in healing cutaneous wounds.
- Fislov et al. 2010. J Virol. 84(17):8691-9. PMID: 20573828.
- Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.
- Satish et al. 2010. PLoS One. 5(4):e10063. PMID: 20442790.
- Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility.
