Cat. #155097
Anti-AvW-5 (von Willebrand Factor) [MBC 121.1]
Cat. #: 155097
Sub-type: Primary antibody
Unit size: 100 ug
Target: von Willebrand Factor
Class: Monoclonal
Application: ELISA ; IF ; IP ; WB
Reactivity: Dog ; Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Versiti Blood Research Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-AvW-5 (von Willebrand Factor) [MBC 121.1]
- Alternate name: vWf
- Research fields: Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 293 kDa
- Reactivity: Dog ; Human
- Host: Mouse
- Application: ELISA ; IF ; IP ; WB
- Description: Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
- Immunogen: vWf - epitope lies on the C-terminal end of VWF
- Myeloma used: P3X63Ag8.653
- Recommended controls: IgG1
Target Details
- Target: von Willebrand Factor
- Molecular weight: 293 kDa
- Tissue cell line specificity: Mouse
- Target background: Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
Applications
- Application: ELISA ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Jacobi et al. 2012. Blood. 119(19):4543-53. PMID: 22431572.
- Haberichter et al. 2005. Blood. 105(1):145-52. PMID: 15331450.
- Haberichter et al. 2000. Blood. 96(5):1808-15. PMID: 10961880.
- Rosenberg et al. 1998. J Clin Invest. 101(3):613-24. PMID: 9449695.
