AF10 is a putative transcription factor containing a leucine zipper motif
| Institute |
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| Queen Mary University of London |
| Cat. #: | 151280 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Genetics |
| Application: | WB ; ELISA ; FACS ; IHC ; IP ; WB |
| Target: | AF10 |
| Reactivity: | Human ; Mouse |
| Clone: | HAF10 9A5/2 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. Clones HAF10 3A6/2, HAF10 3H10/3 and HAF10 9C6/2 are also available. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
AF10 plays a key role in the survival of uncommitted hematopoietic cells. Chamorro-Garcia et al. 2012. PLoS One. 7(12):e51626. PMID: 23284727. |
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