The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9.
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| Cat. #: | 152766 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell signaling and signal transduction;Tissue-specific biology |
| Application: | WB |
| Target: | activated human matrix metalloproteinase 1 (MMP1) |
| Reactivity: | Human |
| Clone: | 5C10 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | actMMP-1, actMMP1, activated-MMP1, activated MMP1, activated-MMP-1, activated MMP-1, Fibroblast collagenase |
|---|---|
| Product description: | Matrix metalloproteinases (MMPs) are synthesized as inactiveÄÂĂÂ zymogensÄÂĂÂ with a pro-peptide domain that must be removed before theÄÂĂÂ enzymeÄÂĂÂ is active.ÄÂĂÂ MMP1 breaks down the interstitialÄÂĂÂ collagens, types I, II, and III hence itÄÂĂÂ is an important feature of development, morphogenesis, tissue repair andÄÂĂÂ remodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Molecular weight: | 40 kDa |
| Immunogen: | Ovalbumin-conjugated synthetic peptide; FVLTEGNPRC |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | Matrix metalloproteinases (MMPs) are synthesized as inactivezymogenswith a pro-peptide domain that must be removed before theenzymeis active.MMP1 breaks down the interstitialcollagens, types I, II, and III hence itis an important feature of development, morphogenesis, tissue repair andremodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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