#152766

Anti-activated MMP1 [5C10]

Cat. #152766

Anti-activated MMP1 [5C10]

Cat. #: 152766

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: activated human matrix metalloproteinase 1 (MMP1)

Class: Monoclonal

Application: WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-activated MMP1 [5C10]
  • Alternate name: actMMP-1, actMMP1, activated-MMP1, activated MMP1, activated-MMP-1, activated MMP-1, Fibroblast collagenase
  • Research fields: Cancer;Cell signaling and signal transduction;Tissue-specific biology
  • Clone: 5C10
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 40 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: WB
  • Description: Matrix metalloproteinases (MMPs) are synthesized as inactive zymogens with a pro-peptide domain that must be removed before the enzyme is active. MMP1 breaks down the interstitial collagens, types I, II, and III hence it is an important feature of development, morphogenesis, tissue repair and remodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9.
  • Immunogen: Ovalbumin-conjugated synthetic peptide; FVLTEGNPRC
  • Isotype: IgG1 kappa
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: Activated recombinant MMP-1

Target Details

  • Target: activated human matrix metalloproteinase 1 (MMP1)
  • Molecular weight: 40 kDa
  • Tissue cell line specificity: Activated recombinant MMP-1
  • Target background: Matrix metalloproteinases (MMPs) are synthesized as inactivezymogenswith a pro-peptide domain that must be removed before theenzymeis active.MMP1 breaks down the interstitialcollagens, types I, II, and III hence itis an important feature of development, morphogenesis, tissue repair andremodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9.

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C