| Inventor | Institute |
|---|---|
| Jorgen Fogh, Germain Trempe | Memorial Sloan-Kettering Cancer Center (MSK) |
| SKU: | 161910 |
|---|---|
| Product description: | Malme-3M is a malignant human melanoma cell line that displays fibroblast-like morphology and grows in mixed culture (adherent-suspension). This cell line has been shown to be dependent upon micropthalmia-associated transcription factor (MITF) activity for growth and survival. Malme-3M cells form tumours when injected into immunocompromised mice. These cells express mutant B-Raf (V600E) and wildtype N-Ras. |
| Gender: | Male |
| Cat. #: | 161910 |
|---|---|
| Cancer types: | Lung cancer |
| Organism: | Human |
| Tissue: | Skin |
| Gender: | Male |
| Morphology: | Mixed |
| Growth properties: | Mixed: adherent and suspension |
| Cancer Types In Detail: | Malignant Melanoma |
| Primary citation: | Fogh J et al. 1977. Journal of the National Cancer Institute. 59: 221-226.PMID: 327080. |
| Storage conditions: | Vapor phase of liquid nitrogen. Storage at -70° C will result in loss of viability. |
|---|---|
| Shipping conditions: | Dry Ice |
| Growth medium: | Iscove’s Modified Dulbecco’s Medium supplemened with 20% FBS |
| Temperature: | 37° C |
| Atmosphere: | 95% Air, 5% CO2 |
| Storage medium: | Culture medium 95%; DMSO, 5% |
| Biosafety level: | 1 |
| References: |
Fogh J et al. 1977. Journal of the National Cancer Institute. 59: 221-226.PMID: 327080. Xing F et al. 2012. Oncogene. 31: 446-457. PMID: 21725359. Ma J et al. 2013. PLoS One. 8: e73261. PMID: 24015299. |
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