VLS-VSCC cell line
A novel spontaneously immortalized cell line established from vulva squamous cell carcinoma associated with lichen sclerosus
Contributors
| Inventor | Institute |
|---|---|
| Daniela Elena Costea ; Harsh Dongre ; Line BjÄÂrge | Haukeland University Hospital; University of Bergen |
| SKU: | 160853 |
|---|---|
| Product description: | A novel spontaneously immortalized cell line established from vulva squamous cell carcinoma associated with lichen sclerosus. Currently, there are no in vitro models to study VSCC-VLS. This is the first cell line modelling this disease. |
| Alternate name: | UB-VCC1 |
| Conditional: | No |
| Production details: | Spontaneously immortalized, i.e without any additional genetic alterations |
| Cellosaurus ID: | CVCL_YD88 |
| Disease: | Cancer |
| Cat. #: | 160853 |
|---|---|
| Unit size: | 1×10^6 cells / vial |
| Cancer types: | Cervical cancer |
| Research Fields: | Cancer |
| Organism: | Human |
| Model: | Cancer Model |
| Growth properties: | Doubling time: 18.90 ÄÂ? 0.53 hours |
| Cancer Types In Detail: | Vulvar lichen sclerosus and vulva squamous cell carcinoma |
| Format: | Frozen |
|---|---|
| Shipping conditions: | Dry Ice |
| Growth medium: | Spontaneously immortalized, i.e without any additional genetic alterations DMEM/Nutrient Mixture F-12 Ham medium (D8437, Sigma) supplemented with 10% NBCS, 1X Insulin-Transferrin-Selenium (41400-04, Thermofisher Scientific), 0.4 ug/mL hydrocortisone (H0888, Sigma), 50ug/mL L-ascorbic acid (A7631, Sigma), and 10ng/mL epidermal growth factor (E9644, Sigma) Doubling time: 18.90 ÄÂ? 0.53 hours |
| References: |
Dongre et al. 2020. Exp Cell Res. 386(1):111684. PMID: 31654625. |
|---|
Images
View Gallery
Product Images
Isolation and characterization of vulva cancer cells (VCC1). Representative phase contrast images showing outgrowth of cancer cells at day 4 (a); day 6 (b) and day 9 (c) respectively. Morphology of VCC1 is mainly polygonal (d). Scale bar- 50??m. Image modified from https
