Cat. #160436
UM-UC-1 (Human bladder transitional cell carcinoma) cell line
Cat. #: 160436
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Lymphatic Tissue
Disease: Cancer
Model: Cancer Model
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: H. Grossman ; Anita Sabichi
Institute: University of Michigan
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: UM-UC-1 (Human bladder transitional cell carcinoma) cell line
- Alternate name: UM-UC-1; UMUC1; University of Michigan-Urothelial Carcinoma-1
- Cancer: Genitourinary cancer
- Cancers detailed: Human bladder translational cell carcinoma
- Research fields: Cancer
- Organism: Human
- Tissue: Lymphatic Tissue
- Disease: Cancer
- Growth properties: Adherent
- Model: Cancer Model
- Description: UM-UC-1 was isolated from a human transitional cell carcinoma (grade II) originating from a bladder cancer metastasis (lymph) of a 26-year old black male. Tumourigenicity studies in nude mice revealed the UM-UC-1 produced tumours, 1-1.5 cm in diameter in < 3 weeks. UM-UC-1 showed strong over expression of nuclear staining for p53 by immunochemical analysis. UM-UC-1 was more resistant to adenoviral gene transduction than several of the other cells evaluated. This cell line has one of the highest levels of coxsackie adenovirus receptor (CAR) expression of the cells tested. UM-UC-1 is among a panel of 12 human urothelial cancer cell lines deposited by the University of Michigan.
Handling
- Format: Frozen
- Growth medium: Cells were grown in Dulbecco's modified Eagle's medium (DMEM) containing 10% heat inactivated Fetal Bovine Serum (FBS) and were supplemented with 1% penicillin and streptomycin at 37?°C in 5% CO2 environment.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: UM-UC-4 (Human adenocarcinoma lymph node metastasis) cell line ; UM-UC-3 (Human bladder transitional cell carcinoma) cell line ; UM-UC-5 (Human squamous cell carcinoma of the bladder) cell line ; UM-UC-7 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-9 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-10 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-11 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-13 (Human...
References
- Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639.
- Grossman et al. 1984. J Urol. 132(4):834-7. PMID: 6471236.
