These ALCAM-ALCAM interactions have been implicated in the development and maintenance of tissue architecture and tumor progression.
| Inventor | Institute |
|---|---|
| Carl G. Figdor | Radboud University Medical Center (UMC) |
| Cat. #: | 160391 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Immunology |
| Application: | FACS ; IP ; WB |
| Target: | Activated leukocyte cell adhesion molecule |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD166 antigen, MEMD |
|---|---|
| Product description: | ALCAM, or CD166, is a cell adhesion molecule that mediates heterotypic cell-cell contacts via its interaction with CD6, resulting in initiation and stabilization of T-cell-dendritic-cell interactions affecting T-cell activation. It also engages in homotypic cell-cell contacts. These ALCAM-ALCAM interactions have been implicated in the development and maintenance of tissue architecture and tumor progression. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | K562-ALCAM |
| Target background: | ALCAM, or CD166, is a cell adhesion molecule that mediates heterotypic cell-cell contacts via its interaction with CD6, resulting in initiation and stabilization of T-cell-dendritic-cell interactions affecting T-cell activation. It also engages in homotypic cell-cell contacts. These ALCAM-ALCAM interactions have been implicated in the development and maintenance of tissue architecture and tumor progression. |
|---|
| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
| References: |
Te Riet et al. 2007. J Cell Sci. 120(Pt 22):3965-76. PMID: 17971418. |
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