Cat. #157892
Anti-CLEC16A [7A4]
Cat. #: 157892
Unit size: 100 ug
Availability: 10-12 weeks
Target: C-Type Lectin Domain Containing 16A
Class: Monoclonal
Application: ELISA ; FACS ; IF ; WB
Reactivity: Human
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: The University of British Columbia
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CLEC16A [7A4]
- Alternate name: CLEC16A (also known as KIAA35)
- Research fields: Disease (not cancer);Immunology;Neurobiology
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Rat
- Application: ELISA ; FACS ; IF ; WB
- Description: Antibody against CLEC16A (specifically binds to C-terminal human peptide CLEC16A954-980: VIVNETEADSKPSKNVARSAAVETASL) CLEC16A is a cytosolic protein which is differentially expressed in human immune cells and is known to be highly expressed on B-lymphocytes, natural killer (NK) and dendritic cells. CLEC16A gene has been linked to several autoimmune diseases, including Addison's disease, diabetes melllitus, Crohn's disease, primary biliary cirrhosis, juvenile idiopathic arthritis, rheumatoid arthritis and multiple sclerosis. . CLEC16A has been shown to regulate various immune pathways including directly regulating leukocyte antigen class II pathway in antigen presenting cells, autophagy, mitophagy, and NK cell cytotoxicity.
- Immunogen: 27-mer C-terminal human peptide (CLEC16A 954-980: VIVNETEADSKPSKNVARSAAVETASL) linked to KLH
- Recommended controls: IgG2b
Target Details
- Target: C-Type Lectin Domain Containing 16A
- Target background: antibody against CLEC16A (specifically binds to C-terminal human peptide CLEC16A954-980: VIVNETEADSKPSKNVARSAAVETASL) CLEC16A is a cytosolic protein which is differentially expressed in human immune cells and is known to be highly expressed on B-lymphocytes, natural killer (NK) and dendritic cells. CLEC16A gene has been linked to several autoimmune diseases, including Addison's disease, diabetes melllitus, Crohn's disease, primary biliary cirrhosis, juvenile idiopathic arthritis, rheumatoid arthritis and multiple sclerosis. . CLEC16A has been shown to regulate various immune pathways including directly regulating leukocyte antigen class II pathway in antigen presenting cells, autophagy, mitophagy, and NK cell cytotoxicity.
Applications
- Application: ELISA ; FACS ; IF ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
References
- van Luijn et al. 2015. Brain. 138(Pt 6):1531-47. PMID: 25823473.
