Anti-IAb +Ea peptide [YAe]

Monoclonal antibody which binds YAe antigen on B cells and antigen presenting cells.

Contributors

Institute
Yale University
SKU: 155244
Product description: Monoclonal antibody which binds YAe antigen on B cells and antigen presenting cells. Background and Research Application This YAe antibody reacts with a class II major histocompatibility complex (MHC) self Ea peptide (peptide 52-68) bound to I-Ab molecules. The YAe antibody binds to an epitope expressed on a subset of class II I-Ab molecules in strains that also express class II I-Eb. This epitope is found on peripheral B cells and on cells in the thymic medulla, but not thymic cortical epit…
Conjugation: Unconjugated
Immunogen: P14483
Immunogen Uniprot ID: P14483
Cat. #: 155244
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology
Target: MHC Class II (IA/IE)
Class: Monoclonal
Target background: Monoclonal antibody which binds YAe antigen on B cells and antigen presenting cells. Background and Research Application This YAe antibody reacts with a class II major histocompatibility complex (MHC) self Ea peptide (peptide 52-68) bound to I-Ab molecules. The YAe antibody binds to an epitope expressed on a subset of class II I-Ab molecules in strains that also express class II I-Eb. This epitope is found on peripheral B cells and on cells in the thymic medulla, but not thymic cortical epit…
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
Shipping conditions: Dry ice
References:

Bonacina et al. 2018. Nat Commun. 9(1):3083. PMID: 30082772.

Rouhani et al. 2015. Nat Commun. 6:6771. PMID: 25857745.

Michelet et al. 2015. J Immunol. 194(5):2079-88. PMID: 25637027.

Murphy et al. 1989. Nature. 338(6218):765-8. PMID: 2469959.

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