TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation.
| Inventor | Institute |
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| Royal McGraw | University of Georgia |
| SKU: | 153928 |
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| Product description: | Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer’s and cancer. |
| Alternate name: | TNF-? |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Immunogen: | Protein |
| Cat. #: | 153928 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Apoptosis and autophagy; Cell signaling and signal transduction |
| Application: | WB ; ELISA ; IP |
| Target: | Tumor Necrosis Factor- alpha |
| Reactivity: | Horse |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer’s and cancer. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
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