Anti-Integrin Beta 3a (GPIIIa, CD61) [MBC 319.4]

Glycoprotein IIb/IIIa, also known as integrin aIIb?Ÿ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann’s thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.

Contributors

Inventor Institute
Richard Aster Versiti Blood Research Institute
Cat. #: 153748
Unit size: 100 ug
Research Fields: Immunology
Application: FACS
Target: Integrin Beta 3a (GPIIIa, CD61) 
Host: Mouse
Class: Monoclonal
Alternate name: CD-61
Product description: Glycoprotein IIb/IIIa, also known as integrin aIIb?Ÿ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Conjugation: Unconjugated
Isotype: IgG2b
Molecular weight: ~ 86-87 kDa
Immunogen: EGF repeats
Target background: Glycoprotein IIb/IIIa, also known as integrin aIIb?Ÿ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Format: Liquid
Concentration: 0.9-1.1mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice

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