Anti-Integrin Beta 3 (GPIIIa, CD61) [AP-2]

Contributors

Inventor Institute
Richard Aster Versiti Blood Research Institute
SKU: 153745
Product description: Glycoprotein IIb/IIIa, also known as integrin aIIb?Ÿ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann’s thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Alternate name: CD-61
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: Human platelet
Cat. #: 153745
Unit size: 100 ug
Research Fields: Immunology
Application: ELISA ; FACS
Target: Integrin Beta 3 (GPIIIa, CD61) 
Host: Mouse
Class: Monoclonal
Target background: Glycoprotein IIb/IIIa, also known as integrin aIIb?Ÿ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann’s thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Format: Liquid
Concentration: 0.9-1.1mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Pidard et al. 1983. J Biol Chem. 258(20):12582-6. PMID: 6226659.

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.

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