SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
| Inventor | Institute |
|---|---|
| Lionel Crawford | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 153337 |
|---|---|
| Product description: | SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Molecular weight: | 94 kDa |
| Immunogen: | SV40 large and small T-antigen |
| Cat. #: | 153337 |
|---|---|
| Provenance and Ownership: | The Anti-SV40T [PAb419] is owned by Cancer Research UK. CancerTools supplies the Anti-SV40T [PAb419] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-SV40T [PAb419] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | WB ; IF ; IP |
| Target: | N-terminal domain of SV40 large and small T-antigen |
| Reactivity: | Virus |
| Clone: | PAb419 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. |
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| Format: | Liquid |
|---|---|
| Storage conditions: | -80° C |
| Shipping conditions: | Dry ice |
| References: |
Goolsby et al. 1991. Cytometry. 12(8):748-56. PMID: 1665408. Viral and cellular oncogene expression during progressive malignant transformation of SV40 transformed human fibroblasts. Monoclonal antibodies specific for simian virus 40 tumor antigens. Harlow et al. 1981. J Virol. 39(3):861-9. PMID: 6169844. |
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