Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.
| Inventor | Institute |
|---|---|
| Margaret Goodall | University of Birmingham |
| Cat. #: | 153232 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | IHC |
| Target: | Broad lecocyte but Germinal Centre negative |
| Reactivity: | Human |
| Clone: | BU90 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | leucocytes; white blood cells; WBCs |
|---|---|
| Product description: | Leucocytes are white blood cells which circulate in the blood and body fluids involved in counteracting foreign substances and disease. There are several types, including lymphocytes, granulocytes, and monocytes, which are all amoeboid cells containing a nucleus. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Peripheral blood lymphocytes |
| Target background: | Leucocytes are white blood cells which circulate in the blood and body fluids involved in counteracting foreign substances and disease. There are several types, including lymphocytes, granulocytes, and monocytes, which are all amoeboid cells containing a nucleus. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | '-15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Leucocyte Typing VI, 1998, Kishimoto_T. Garland Publishing, NY. |
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