SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
| Inventor | Institute |
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| Lionel Crawford | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 152928 |
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| Product description: | SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. |
| Conjugation: | Unconjugated |
| Isotype: | IgG3 |
| Immunogen: | SV40 transformed mouse cells |
| Cat. #: | 152928 |
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| Provenance and Ownership: | The Anti-SV40T [Pab 430] is owned by Cancer Research UK. CancerTools supplies the Anti-SV40T [Pab 430] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-SV40T [Pab 430] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Microbiology |
| Application: | IP ; RIA ; WB |
| Target: | Simian virus (SV40) T antigen (large T and small T antigen) |
| Reactivity: | Virus |
| Clone: | Pab 430 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Kennedy et al. 1985. J Exp Med. 161(6):1432-49. PMID: 2409201. Suppression of in vivo tumor formation induced by simian virus 40-transformed cells in mice receiving antiidiotypic antibodies. Harlow et al. 1981. J Virol. 39(3):861-9. PMID: 6169844. Monoclonal antibodies specific for simian virus 40 tumor antigens. |
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