This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B).
| Inventor | Institute |
|---|---|
| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 152693 |
|---|---|
| Product description: | Cdk2 is a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). |
| Alternate name: | Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; P33 Protein Kinase; CDKN2; CDC2-Related Protein Kinase; P33(CDK2) |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Xenopus Cdk2 |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 152693 |
|---|---|
| Provenance and Ownership: | The Anti-Cdk2 [C15.2] is owned by Cancer Research UK. CancerTools supplies the Anti-Cdk2 [C15.2] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Cdk2 [C15.2] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell biology; Genetics |
| Application: | ELISA ; IHC ; IF ; WB |
| Target: | Cdk2 |
| Reactivity: | Xenopus laevis |
| Clone: | C15.2 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Cdk2 is a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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