#152156

Anti-Cytochrome P450 4A11 [M25-P2A10]

Cat. #152156

Anti-Cytochrome P450 4A11 [M25-P2A10]

Cat. #: 152156

Sub-type: Primary antibody

Unit size: 100 ug

Target: Cytochrome P450, family 4, subfamily A, polypeptide 11 (CYP4A11)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Drosophila ; Human ; Mouse ; Rat ; Xenopus laevis

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Cytochrome P450 4A11 [M25-P2A10]
  • Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
  • Clone: M25-P2A10
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Drosophila ; Human ; Mouse ; Rat ; Xenopus laevis
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: CYP4A11 is upregulated in primary and metaststic CRC tumours compared to normal colon mucosa.
  • Immunogen: Peptide Sequence KNGIHLRLR (amino acids 499 507)
  • Isotype: IgG1 kappa
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC-Human liver

Target Details

  • Target: Cytochrome P450, family 4, subfamily A, polypeptide 11 (CYP4A11)
  • Tissue cell line specificity: ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC-Human liver
  • Target background: CYP4A11 is upregulated in primary and metaststic CRC tumours compared to normal colon mucosa.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Alnabulsi et al. 2017. Br J Cancer. :. PMID: 28557975.
  • The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.
  • Alnabulsi et al. 2016. Characterisation of Arachidonic Acid Metabolising Enzymes in Colorectal Cancer J Pathol. 240 Suppl 1:S1-S48. PMID: 27747872
  • Nottingham Pathology 2016. 9th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 28 June - 1 July 2016.