Cat. #152111
T47D/S5 Cell Line
Cat. #: 152111
Sub-type: Continuous
Unit size: 1x10^6 cells / vial
Availability: 10-12 weeks
Organism: Human
Tissue: Breast
Disease: Cancer
Model: Tumour line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Anne Lykkesfeldt
Institute: Danish Cancer Society, Denmark
Primary Citation: Kirkegaard et al. 2014. Cancer Lett. 344(1):90-100. PMID: 24513268.
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: T47D/S5 Cell Line
- Cancer: Breast cancer
- Cancers detailed: Breast cancer
- Research fields: Cancer;Drug development
- Tool sub type: Continuous
- Parental cell: T47D
- Organism: Human
- Tissue: Breast
- Disease: Cancer
- Model: Tumour line
- Description: The T47D/S5 cell line is a control cell line for the fulvestrant (Faslodex) resistant T47D/182R-1 and T47D/182R-2 cell lines. T47D/S5 is adherent and the morphology is polygonal epithelial. The cell passage number is 155 (AL3043, AL3044). T47D/S5 cells express oestrogen receptor alpha and progesterone receptor. This cell line allows the study of the mechanisms involved in fulvestrant resistant breast cancer cell growth.
- Application: Determining molecular mechanisms around fulvestrant resistance
- Production details: T47D/S5 cells grows continuously in presence of 5% fetal calf serum.
- Cellosaurus id: CVCL_1D46
Target Details
- Target: Oestrogen receptor
Applications
- Application: Determining molecular mechanisms around fulvestrant resistance
Handling
- Format: Frozen
- Passage number: Passage 155 (AL3043, AL3044)
- Growth medium: Phenol red free RPMI 1640 + 5% FCS + glutamax + 8ug Insulin/ml
- Temperature: 37° C
- Atmosphere: 5% CO2
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
References
- Larsen et al. 2015. PLoS One. 10(2):e0118346. PMID: 25706943.
- Larsen et al. 2015. BMC Cancer. 15(1):1-15. PMID: 25885472.
- Thrane et al. 2014. Oncogene. 34(32): 4199-4210. PMID: 25362855.
- Kirkegaard et al. 2014. Cancer Lett. 344(1):90-100. PMID: 24513268.
