TRF2 (also known as TERF2), is a component of the telomere nucleoprotein complex.
| Inventor | Institute |
|---|---|
| Stephen West | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151823 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Genetics |
| Application: | ChIP ; IF ; WB |
| Target: | human TRF2 |
| Reactivity: | Human |
| Clone: | SWE38 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Product description: | TRF2 (also known as TERF2), is a component of the telomere nucleoprotein complex. Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. |
|---|---|
| Conjugation: | Unconjugated |
| Immunogen: | His tagged full length recombinant TRF2 (from baculovirus) |
| Target background: | TRF2 (also known as TERF2), is a component of the telomere nucleoprotein complex. Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | Whole serum |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Tarsounas et al. 2004. Cell. 117(3):337-47. PMID: 15109494. Telomere maintenance requires the RAD51D recombination/repair protein. Tarsounas et al. 2003. Oncogene. 22(8):1115-23. PMID: 12606939. BRCA2-dependent and independent formation of RAD51 nuclear foci. |
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