Distinguishes between sub-species of human interferon alpha and can be used to detect interferon oligomers. Neutralises anti-viral activity of interferon.
| Inventor | Institute |
|---|---|
| Joyce Taylor-Papadimitriou | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151744 |
|---|---|
| Product description: | Distinguishes between sub-species of human interferon alpha and can be used to detect interferon oligomers. Neutralises anti-viral activity of interferon. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Molecular weight: | 18-25 kDa |
| Immunogen: | Human interferon (HuIFN) produced by Namalwa cells (HuIFN-aN) |
| Myeloma used: | P3X63Ag8.653 |
| Cat. #: | 151744 |
|---|---|
| Provenance and Ownership: | The Anti-Interferon [ST126] is owned by Cancer Research UK. CancerTools supplies the Anti-Interferon [ST126] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Interferon [ST126] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Immunology |
| Application: | Fn |
| Target: | Human interferon alpha subspecies |
| Reactivity: | Human |
| Clone: | ST126 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Distinguishes between sub-species of human interferon alpha and can be used to detect interferon oligomers. Neutralises anti-viral activity of interferon. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Shearer et al. 1992. Int J Oncol. 1(3):303-12. PMID: 21584547. Monoclonal-antibodies to huifn-alpha species applied to the study of IFN-receptor interaction indicate that receptor down-regulation does not occur in daudi cells. Taylor-Papadimitriou et al. 1987. J Immunol. 139(10):3375-81. PMID: 2445813. Epitopes of human interferon-alpha defined by the reaction of monoclonal antibodies with alpha interferons and interferon analogues. Shearer et al. 1984. J Immunol. 133(6):3096-101. PMID: 6491281. Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers. |
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