Anti-WSTF [WSTF]

The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its Fn motifs include a PHD zinc finger motif followed by a bromodomain.

Contributors

Inventor Institute
Patrick Varga-Weisz Marie Curie Research Institute
SKU: 151586
Product description: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its functional motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The droso…
Conjugation: Unconjugated
Molecular weight: 170 kDa
Immunogen: Peptide coupled to keyhole limpet hemocyanin.
Cat. #: 151586
Provenance and Ownership: The Anti-WSTF [WSTF] is owned by Cancer Research UK. CancerTools supplies the Anti-WSTF [WSTF] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-WSTF [WSTF] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Breast cancer
Research Fields: Genetics
Application: IF ; IP ; WB
Target: Williams Syndrome Transcription Factor (WSTF)
Reactivity: Human ; Mouse
Clone: WSTF
Host: Rabbit
Class: Polyclonal
Target background: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its Fn motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The drosophila Ac…
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: Whole serum
Storage conditions: -80° C
Shipping conditions: Dry ice
References:

Sarshad et al. 2013. PLoS Genet. 9(3):e1003397. PMID: 23555303.

Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression.

Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.

WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.

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Adapted from Sarshad et al. 2013. PLoS Genet. 9(3)

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