Cat. #151586
Anti-WSTF [WSTF]
Cat. #: 151586
Sub-type: Primary antibody
Unit size: 100 ug
Target: Williams Syndrome Transcription Factor (WSTF)
Class: Polyclonal
Application: IF ; IP ; WB
Reactivity: Human ; Mouse
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Patrick Varga-Weisz
Institute: Marie Curie Research Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-WSTF [WSTF]
- Cancer: Breast cancer
- Cancers detailed: Breast cancer
- Research fields: Genetics
- Clone: WSTF
- Tool sub type: Primary antibody
- Class: Polyclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 170 kDa
- Reactivity: Human ; Mouse
- Host: Rabbit
- Application: IF ; IP ; WB
- Description: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its functional motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The droso...
- Immunogen: Peptide coupled to keyhole limpet hemocyanin.
- Recommended controls: ES, NIH 3T3, and HeLa cells
Target Details
- Target: Williams Syndrome Transcription Factor (WSTF)
- Molecular weight: 170 kDa
- Tissue cell line specificity: Sheep
- Target background: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its Fn motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The drosophila Ac...
Applications
- Application: IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: Whole serum
- Storage conditions: -80° C
- Shipping conditions: Shipping at 4° C
References
- Sarshad et al. 2013. PLoS Genet. 9(3):e1003397. PMID: 23555303.
- Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression.
- Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.
- WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.
