Cat. #151460
Anti-ATMIN [ATMIN 11F4]
Cat. #: 151460
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Ataxia Telangiectasia Mutated Interacting protein (ATMIN, ASCIZ)
Class: Monoclonal
Application: IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-ATMIN [ATMIN 11F4]
- Research fields: Genetics
- Clone: ATMIN 11F4
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IF ; IP ; WB
- Description: The checkpoint kinase ATM (ataxia telangiectasia mutated) transduces genomic stress signals to halt cell cycle progression and promote DNA repair in response to DNA damage. ATMIN (ATM INteracting protein) is an essential cofactor for ATM. ATMIN interacts with ATM through a C-terminal motif, which is also present in Nijmegen breakage syndrome (NBS) 1.
- Immunogen: Synthetic peptide
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
- Recommended controls: 293T Cells
Target Details
- Target: Ataxia Telangiectasia Mutated Interacting protein (ATMIN, ASCIZ)
- Tissue cell line specificity: 293T Cells
- Target background: The checkpoint kinase ATM (ataxia telangiectasia mutated) transduces genomic stress signals to halt cell cycle progression and promote DNA repair in response to DNA damage. ATMIN (ATM INteracting protein) is an essential cofactor for ATM. ATMIN interacts with ATM through a C-terminal motif, which is also present in Nijmegen breakage syndrome (NBS) 1.
Applications
- Application: IF ; IP ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -80° C
- Shipping conditions: Shipping at 4° C
References
- Kanu et al. 2007. EMBO J. 26(12):2933-41. PMID: 17525732.
- ATMIN defines an NBS1-independent pathway of ATM signalling.
