Cat. #151431
Anti-CD21 [BU32]
Cat. #: 151431
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Complement component (3d/Epstein Barr virus) receptor 2 (CR2, CD21)
Class: Monoclonal
Application: WB ; FACS ; IHC ; IF
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD21 [BU32]
- Alternate name: Complement Component 3d Receptor 2; Epstein-Barr Virus Receptor 2; Complement C3d Receptor; EBV Receptor; C3DR; CD21 Antigen; CVID7; SLEB9; CD21; Cr2; CR
- Research fields: Cell signaling and signal transduction;Immunology
- Clone: BU32
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: WB ; FACS ; IHC ; IF
- Description: CR2 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CR2 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CR2 expression is also gradually lost after stimulation of B cells in vitro. CR2 functions as a receptor for C3d, C3dg and iC3b Complement components and for EBV and for IFN alpha. CR2 binds to CD23 and ...
- Immunogen: Myeloma cell line Rob
- Isotype: IgG1
- Myeloma used: NS0
Target Details
- Target: Complement component (3d/Epstein Barr virus) receptor 2 (CR2, CD21)
- Tissue cell line specificity: Mouse
- Target background: CR2 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CR2 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CR2 expression is also gradually lost after stimulation of B cells in vitro. CR2 functions as a receptor for C3d, C3dg and iC3b Complement components and for EBV and for IFN alpha. CR2 binds to CD23 and ...
Applications
- Application: WB ; FACS ; IHC ; IF
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Knapp, W. et al. eds. 1989. Leucocyte Typing IV Oxford University Press. ISBN-13: 978-0192618672
- Leucocyte Typing III 1987. ISBN-13: 978-0192615527
- Leucocyte Typing V 1995. ISBN-13: 978-0192623768
- Leucocyte Typing VI 1998. Garland Publishing NY. ISBN-13: 978-0815327455
- Ling, NR., Brown, B., Immunobiology (1992) 185(2-4) pp403-14
- Jackson et al. 2020. BMC Genet. 21(1):101. PMID: 32907542.
- Herishanu et al. 2013. J Immunol. 190(2):784-93. PMID: 23241880.
- Masilamani et al. 2004. Rheu...
