SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
| Inventor | Institute |
|---|---|
| David Lane | University of Dundee |
| Cat. #: | 151410 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Microbiology |
| Application: | IHC ; IF ; IP ; WB |
| Target: | SV40 small T antigen |
| Reactivity: | Virus |
| Clone: | pab 280 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | A purified Pab 419-small T complex |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Berg et al. 2010. J Med Virol. 82(9):1594-9. PMID: 20648615. Enterovirus markers and serum CXCL10 in children with type 1 diabetes. Montano et al. 1989. J Virol. 63(7):3128-34. PMID: 2542620. Monoclonal antibody analysis of simian virus 40 small t-antigen expression in infected and transformed cells. Montano et al. 1984. J Virol. 51(3):760-7. PMID: 6088798. Monoclonal antibody to simian virus 40 small t. |
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