LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The Fn role of LILRB1 has not been fully elucidated.
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| Cat. #: | 151378 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | FACS ; IP ; WB |
| Target: | Leukocyte Immunogolobulin-like Receptor subfamily B member 1 (LILRB1, CD85) |
| Reactivity: | Human |
| Clone: | VMP55 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The functional role of LILRB1 has not been fully elucidated. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Molecular weight: | 120 kDa |
| Immunogen: | Hairy cell leukaemia cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The Fn role of LILRB1 has not been fully elucidated. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Lamar et al. 2010. Blood. 115(16):3278-86. PMID: 20194892. Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages. Prod'homme et al. 2007. J Immunol. 178(7):4473-81. PMID: 17372005. The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells. Banham et al. 1999. J Leukoc Biol. 65(6):841-5. PMID: 10380908. Identification of the CD… |
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