Anti-FCGR3 [DJ130c] mAb

FCGR3 mediates phagocytosis and antibody-dependent cell-mediated cytotoxicity.

Contributors

Inventor Institute
Jacqueline Cordell University of Oxford
Cat. #: 151351
Unit size: 100 ug
Research Fields: Cell biology;Immunology;Stem cell biology
Application: FACS ; IHC ; IP ; WB
Target: Fc gamma receptor III (FCGR3, CD16, Leu II)
Reactivity: Human
Clone: DJ130c
Host: Mouse
Class: Monoclonal
Product description: FCGR3 mediates phagocytosis and antibody-dependent cell-mediated cytotoxicity. It is expressed on neutorphils, NK cells and macrophages
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: CD16
Myeloma used: P3/NS1/1-Ag4.1
Target background: FCGR3 mediates phagocytosis and antibody-dependent cell-mediated cytotoxicity. It is expressed on neutorphils, NK cells and macrophages
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Storage conditions: '-15° C to -25° C
Shipping conditions: Dry ice
References:

Schmidt RE (1993) CD16 cluster workshop report. In Schlossman SF, et al (eds) Leucocyte Typing V, Vol 1, Oxford University Press, Oxford, New York and Tokyo, p 805-806 Zhu X et al. 1998. J Immunol 161:2574-9. PMID: 9725258 HĂśnig M et al. J Leukoc Biol. 1999 Sep

66(3):429-36. PMID: 10496313

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