Fibrin (also called Factor Ia) is a fibrous protein involved in the clotting of blood, and is non-globular. It is a fibrillar protein that is polymerised to form a “mesh” that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site.
| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151172 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Tissue-specific biology |
| Application: | IF ; FACS ; IF ; IP ; RIA |
| Target: | Fibrin alpha chain |
| Reactivity: | Human |
| Clone: | UC45 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Fibrin (also called Factor Ia) is a fibrous protein involved in the clotting of blood, and is non-globular. It is a fibrillar protein that is polymerised to form a "mesh" that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Molecular weight: | 45 kDa |
| Immunogen: | Human acute monoblastic leukemia cells. |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Fibrin (also called Factor Ia) is a fibrous protein involved in the clotting of blood, and is non-globular. It is a fibrillar protein that is polymerised to form a "mesh" that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Wu et al. 2013. Am J Nucl Med Mol Imaging. 3(5):446-55. PMID: 24116353. Molecular MRI of atherosclerotic plaque progression in an ApoE(-/-) mouse model with a CLT1 peptide targeted macrocyclic Gd(III) chelate. Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201. Monoclonal antibodies differentiating between monocytic and nonmonocytic variants of AML. Hogg et al. 1983. J Exp Med. 157(2):473-85. PMID: 6822786. Human monocytes are associated with the formation of fibrin. Hogg et al. 1981. Cell. 24(3):875-84. PMID: 6788378. Monoclonal antibody with specificity for monocytes and neurons. |
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