ST29 distinguishes between sub-species of human INFa and can be used to detect INF oligomers. Neutralises anti-viral activity of INF.
| Inventor | Institute |
|---|---|
| Joyce Taylor-Papadimitriou | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151162 |
|---|---|
| Product description: | ST29 distinguishes between sub-species of human IFNa and can be used to detect IFN oligomers. Neutralises anti-viral activity of IFN. |
| Alternate name: | ADMCKD, ADMCKD1, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 18-25 kDa |
| Immunogen: | Human interferon (HuIFN) produced by Namalwa cells (HuIFN-aN) |
| Myeloma used: | P3X63Ag8.653 |
| Cat. #: | 151162 |
|---|---|
| Provenance and Ownership: | The Anti-IFNa [ST29] is owned by Cancer Research UK. CancerTools supplies the Anti-IFNa [ST29] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-IFNa [ST29] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | ELISA ; Fn |
| Target: | Interferon alpha (IFNa) |
| Reactivity: | Human |
| Clone: | ST29 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | IFNa is a type I interferon that is involved in the innate immune response against viral infections. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Doganay et al. 2017. Integr Biol (Camb). 9(11):857-867. PMID: 29098213. Gainey et al. 2008. J Virol. 82(19):9369-80. PMID: 18667520. A hyperfusogenic F protein enhances the oncolytic potency of a paramyxovirus simian virus 5 P/V mutant without compromising sensitivity to type I interferon. Shearer et al. 1984. J Immunol. 133(6):3096-101. PMID: 6491281. Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers. |
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