Anti-Leu2 [M236]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-Leu2 [M236]
• Alternate name: Integrin Subunit Alpha 2; Alpha 2 Subunit Of VLA-2 Receptor; Platelet Membrane Glycoprotein Ia; CD49 Antigen-Like Family Member B; Collagen Receptor; CD49B; GPIa; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; Human Platelet Alloantigen System 5; Platelet Glycoprotein GPIa; Platelet Antigen Br; VLA-2 Subunit Alpha; CD49b Antigen; HPA-5; VLA-2; VLAA2; BR
• Research fields: Immunology;Stem cell biology
• Clone: M236
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 32 kDa
• Strain: Balb/c
• Reactivity: Human
• Host: Mouse
• Application: IHC ; IP ; RIA
• Description: M236 is useful for the identification of cytotoxic/suppressor cell subpopulation in peripheral blood, elimination of cytotoxic/suppressor cell subpopulation from peripheral blood and bone marrow, elimination of some T cell leukaemias and blocking of cytotoxic activity.
• Immunogen: MOLT 4 cell line.
• Isotype: IgG1
• Myeloma used: P3/NS1/1-Ag4.1
• Recommended controls: human platelets and megakaryocytes

Target Details

• Target: Leu2 (CD8)
• Molecular weight: 32 kDa
• Tissue cell line specificity: human platelets and megakaryocytes
• Target background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells.

Applications

• Application: IHC ; IP ; RIA

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Dry ice

References

• 1st International Workshop on Human Leucocyte Differentiation Antigans (code T67), Paris, November 1982