F20.14 can be used as in vitro markers of terminally differentiated breast lumenal epithelial cells.
| Inventor | Institute |
|---|---|
| Joy Burchell ; Joyce Taylor-Papadimitriou | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151094 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | IHC ; WB |
| Target: | Casein beta subunit |
| Reactivity: | Human |
| Clone: | F20.14 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | F20.14 can be used as in vitro markers of terminally differentiated breast lumenal epithelial cells. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 28 kDa |
| Immunogen: | Purified casein and a-lactalbumin. |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | Caseins are the major proteins found in milk. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.88 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Bonuccelli et al. 2012. Cell Cycle. 11(21):3972-82. PMID: 23047602. The milk protein a-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis. Burchell et al. 1985. Hybridoma. 4(4):341-50. PMID: 3905581. Production and characterization of monoclonal antibodies to human casein. A monoclonal antibody that cross-reacts with casein and alpha-lactalbumin. |
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