YK6 Cell line

Human follicular dendritic cell immortalised with telomerase, dominant negative TP53 and CDK4(R24C). Feeder cells for human B cells.

Contributors

Inventor Institute
Daniel J Hodson, Rebecca Caeser University of Cambridge
Product description: Human follicular dendritic cell immortalised with telomerase, dominant negative TP53 and CDK4(R24C). Feeder cells for human B cells.
Production details: Folicullar dendritic cells (FDC) were isolated from discarded tonsil tissue and then immortalised through retroviral transduction with pBABE_TERT.Hygro, P53DD_Thy1.1, and CDK4_R24C_Thy1.1
Disease: Cancer
Related tools: YK6_CD40L, YK6_CD40L_Il20
Cat. #: 162443
Organism: Human
Tissue: Tonsil
Morphology: Specific dendritic morphology
Growth properties: Adherent
Cancer Types In Detail: Blood cancer
Primary citation: Caeser 2019 Nat Commun PMID: 31586074
Growth medium: RPMI 1640

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