CXCR4-MOR Bivalent Ligand

A novel bivalent ligand that contains two distinct pharmacophores linked through a spacer, one of which will interact with the mu opioid receptor (MOR) and the other with CXCr4. Naltrexone and It1t were selected as the pharmacophores to generate the bivalent probe.

Contributors

Inventor Institute
Yan Zhang Virginia Commonwealth University
Cat. #: 154267
Research Fields: Cell signaling and signal transduction;Drug development
Product description: A novel bivalent ligand that contains two distinct pharmacophores linked through a spacer, one of which will interact with the mu opioid receptor (MOR) and the other with CXCr4. Naltrexone and It1t were selected as the pharmacophores to generate the bivalent probe.

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