HEK293-CEACAM5-Fc cell line

CEACAM-5 is expressed primarily by epithelial cells and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM-1. CEACAM-5 is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumours.

Contributors

Inventor Institute
Bernhard Singer LeukoCom
SKU: 160690
Product description: CEACAM-5 is expressed primarily by epithelial cells and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM-1. CEACAM-5 is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumours. CEACAM-5 is upregulated in a wide variety of human tumours and is a commonly used cancer marker. It promotes tumour cell migration, invasion, adhesion, and metastasis. It al…
Alternate name: Carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, Cluster of Differentiation 66e
Conditional: No
Production details: Overexpression of human CEACAM5-Fc Chimera Protein
Parental cell line: HEK293
Cat. #: 160690
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Research Fields: Cancer;Cell biology;Immunology
Organism: Human
Tissue: Kidney
Model: Transgenic
Growth properties: Adherent
Format: Frozen
Shipping conditions: Dry ice
Growth medium: DMEM + 10% FBS

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