Anti-Myelin Basic Protein (region 119-131) [MBP2]

MBP Clone 2 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP.

Contributors

Institute
BioServ UK Ltd
SKU: 153639
Product description: Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 2 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP.
Alternate name: Myelin basic protein, MBP, 2 kDa microtubule-stabilizing protein, Myelin A1 protein
Conjugation: Unconjugated
Isotype: IgG1
Molecular weight: 13-21 kDa
Immunogen: Recognises bovine MBP, in the region of residues 119-131 (GAEGQRPGFGYGG)
Myeloma used: NS0
Cat. #: 153639
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Brain cancer
Research Fields: Cell biology; Immunology; Neurobiology
Application: ELISA ; IHC ; IF ; IP ; WB
Target: Myelin Basic Protein (region 119-131)
Reactivity: Bovine ; Human ; Guinea Pig ; Pig ; Rat ; Rabbit ; Sheep
Clone: MBP2
Host: Mouse
Class: Monoclonal
Target background: Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 2 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP.
Format: Liquid
Shipping conditions: Dry ice
References:

Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.

Kokjohn et al. 2013. J Neurotrauma. 30(11):981-97. PMID: 23268705.

Neurochemical profile of dementia pugilistica.

Wong et al. 2013. J Neurosci. 33(11):4947-57. PMID: 23486965.

Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation.

Roher et al. 2013. Am J Neurodegener Dis. 2(3):187-207. PMID: 24093083.

Purkin…

Images

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Clone MBP 2 used to detect myelinated structures in MS plaques by IHC-F. (C) recognized all myelinated structures in control brains; whereas no immunoreactivity was detected by EP antiserum (D). The identical vessel in the four photomicrographs is indicated by the asterisks. Source

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