| Inventor | Institute |
|---|---|
| Jenny Southgate ; Ludwik Trejdosiewicz | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151731 |
|---|---|
| Product description: | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 19 restricted ‘in situ’ to differentiated urothelium. Useful in the studies of epithelial cells and tumor origin. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Molecular weight: | 40 kDa |
| Cat. #: | 151731 |
|---|---|
| Provenance and Ownership: | The Anti-Keratin 19 [LAS86] is owned by Cancer Research UK. CancerTools supplies the Anti-Keratin 19 [LAS86] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Keratin 19 [LAS86] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | IHC |
| Target: | Cytokeratin 19 |
| Reactivity: | Human |
| Clone: | LAS86 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 19 restricted ‘in situ’ to differentiated urothelium. Useful in the studies of epithelial cells and tumor origin. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Trejdosiewicz et al. 1988. Struct Funct Cytoskel. 171: 265-271 von Koskull et al. 1984. Hum Genet. 65(3):262-7. PMID: 6199284. Identification of cells from fetal bladder epithelium in human amniotic fluid. |
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