Anti-HRX [HRX107]

The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners

Contributors

Inventor Institute
Jacqueline Cordell University of Oxford
SKU: 151384
Product description: The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners
Conjugation: Unconjugated
Isotype: IgM
Immunogen: Synthetic peptides corresponding to 839-854 of the HRX protein
Myeloma used: P3/NS1/1-Ag4.1
Cat. #: 151384
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Genetics
Application: ChIP ; IHC ; IF ; WB
Target: Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)
Reactivity: Human
Clone: HRX107
Host: Mouse
Class: Monoclonal
Target background: The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Lukaemia through translocations that that result in its fusion with a variety of heterologous partners
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Mueller et al. 2009. PLoS Biol. 7(11):e1000249. PMID: 19956800.

Misguided transcriptional elongation causes mixed lineage leukemia.

Butler et al. 1997. Blood. 89(9):3361-70. PMID: 9129043.

The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures.

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