Anti-HLA-DOB [DOB 10E6/5]

Contributors

Institute
Cancer Research UK, London Research Institute: Lincoln's Inn Fields
SKU: 151729
Product description: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM.
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: C-terminal peptide MHC class II
Myeloma used: Sp2/0-Ag14
Cat. #: 151729
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology
Application: ELISA ; WB
Target: HLA-DOB
Reactivity: Human
Clone: DOB 10E6/5
Host: Mouse
Class: Monoclonal
Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -80° C
Shipping conditions: Dry ice

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