One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| SKU: | 152762 |
|---|---|
| Product description: | Cytochrome P450 2J2 metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney. Localised to the endoplasmic reticulum membrane; microsome membrane. |
| Alternate name: | Arachidonic acid epoxygenase, CYPIIJ2 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Molecular weight: | 58 kDa |
| Immunogen: | Ovalbumin-conjugated synthetic peptide KFTFRPPNNE (C-terminal sequence) |
| Myeloma used: | P3X63Ag8.653 |
| Cat. #: | 152762 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell signaling and signal transduction; Metabolism; Tissue-specific biology |
| Application: | ELISA ; IHC ; WB |
| Target: | Cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2) |
| Reactivity: | Human |
| Clone: | Z9P1G9* A2 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Cytochrome P450 2J2 metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney. Localised to the endoplasmic reticulum membrane; microsome membrane. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
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